期刊
GENERAL HOSPITAL PSYCHIATRY
卷 31, 期 6, 页码 546-554出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.genhosppsych.2009.06.008
关键词
Posttraumatic stress disorder; Severe acute respiratory syndrome; Follow-up study
类别
资金
- Peking Union Medical College Hospital
- National Institutes of Health, Fogarty International Center [D43TW005814]
- National Institute of Mental Health Center [P20MH071897]
Objective: To measure the incidence and impact of posttraumatic stress disorder (PTSD) in a cohort of 70 subjects with severe acute respiratory syndrome (SARS). Methods: Clinical assessments of PTSD were conducted at 2, 7, 10, 20 and 46 months after discharge from medical hospitalization for treatment of SARS. Diagnoses of PTSD were established by a trained psychiatrist using the Chinese Classification of Mental Disorders (CCMD-III) and Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) criteria. To study the impact of PTSD, we used the Impact of Event Scale (IES), Zung Self-Rating Anxiety Scale (SAS), Zung Self-Rating Depression Scale (SDS), Symptom Checklist 90 (SCL-90), Short Form-36 (SF-36 Health Survey) and Social Disability Screening Schedule (SDSS). Results: Of the 68 subjects who finished at least two follow-up interviews, 30 developed PTSD over the study period (44.1%). Scores on IES, SAS, SDS and SCL-90 (P<.0001) were higher, and functional impairment as measured by SF-36 (P<.0001) and SDSS was more severe (P=.0073) for subjects with PTSD. Conclusion: PTSD occurs in a significant percentage of subjects who recover from SARS, and the occurrence of PTSD predicts persistent psychological distress and diminished social functioning in the 4 years after SARS treatment. (C) 2009 Published by Elsevier Inc.
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