4.6 Article

Identification of expressed transposable element insertions in the sequenced genome of Drosophila melanogaster

期刊

GENE
卷 439, 期 1-2, 页码 55-62

出版社

ELSEVIER SCIENCE BV
DOI: 10.1016/j.gene.2009.03.015

关键词

Transposable element; EST; Expression; Drosophila melanogaster; Transposon

资金

  1. Agence Nationale de la Recherche [GIP ANR JC05_49162]
  2. CNRS

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Transposable elements (TEs) are major components of most genomes, and their impact on genome evolution is now well documented. However, the way they affect the transcriptome is still not clearly established. Using the sequenced genome of Drosophila melanogaster and EST libraries, we describe here the TE insertions that are unequivocally transcribed, and we have determined their location in the sequenced genome. We show that most TE families are transcribed, and we have specifically identified 69 expressed TE insertions, half of which are located inside genes, mostly within introns and 5'UTRs. (C) 2009 Elsevier B.V. All rights reserved.

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