4.3 Article

Management of Spastic Disorders of the Esophagus

期刊

出版社

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.gtc.2012.11.002

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Distal esophageal spasm; Achalasia; Jackhammer esophagus; High-resolution manometry; Esophageal motility

资金

  1. National Institutes of Health [R01DK56033]

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The concept of esophageal spastic disorders encompasses spastic achelasia, distal esophageal spasm, and jackhammer esophagus. These are conceptually distinct in that spastic achalasia and distal esophageal spasm are characterized by a loss of neural inhibition, whereas jackhammer esophagus is associated with hypercontractility. Hypercontractility may also occur as a result of esophagogastric junction outflow obstruction or inflammation. The diagnosis of jackhammer esophagus as a primary motility disorder is based on the characteristic manometric findings after ruling out mechanical obstruction and eosinophilic. esophagitis. Despite the differences in pathophysiology among the esophageal spastic disorders, their management is similar.

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