期刊
GASTROENTEROLOGY CLINICS OF NORTH AMERICA
卷 39, 期 3, 页码 529-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.gtc.2010.08.009
关键词
Acid-related disorders; Functional gastrointestinal disorders; Proton pump inhibitors; H-2-receptor antagonists; Prokinetic agents; Serotonergic agents
资金
- AstraZeneca
Medicines are frequently used in the management of acid-related disorders and functional gastrointestinal disorders With the exception of complicated peptic ulcer disease these disorders are not associated with appreciable mortality Drug treatments have consequently been held to the highest standards of safety Some medicines have been withdrawn or restricted based on assessments and perceptions of risk However the risk of serious toxicity is low for most of the agents discussed in this article Assessments are made of the safety and adverse-event profiles of certain drug classes and, where appropriate individual medicines For conditions with a low risk of mortality or serious morbidity clinicians, need to balance the risks of potential adverse events with the anticipated benefits of a successful outcome of specific drug treatment
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