Endomicroscopy of Intestinal Metaplasia and Gastric Cancer

In vivo histologic diagnosis of gastric intestinal metaplasia (GIM) and gastric cancer (GC) can be achieved by confocal laser endomicroscopy (CLE). This review describes the endomicroscopic features of GIM and GC and reviews their clinical applications. Differentiation of phenotypes of GIM and GC by using CLE is also discussed.