期刊
GASTROENTEROLOGY
卷 146, 期 6, 页码 1449-1458出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.gastro.2014.01.052
关键词
Gastrointestinal; HMP; Lumen; Metagenomics; Microbe; Mucosa
资金
- National Institutes of Health [R01 AT004326, UH3 DK083990, U01 CA170930]
- National Institutes of Health (National Institute for Diabetes and Digestive and Kidney Diseases) [DK56338]
- Texas Medical Center Digestive Diseases Center
- BioGaia AB (Stockholm, Sweden)
The human gastrointestinal tract contains distinct microbial communities that differ in composition and function based on their location, as well as age, sex, race/ethnicity, and diet of their host. We describe the bacterial taxa present in different locations of the GI tract, and their specific metabolic features. The distinct features of these specific microbial communities might affect human health and disease. Several bacterial taxa and metabolic modules (biochemical functions) have been associated with human health and the absence of disease. Core features of the healthy microbiome might be defined and targeted to prevent disease and optimize human health.
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