相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Identification of dual mTORC1 and mTORC2 inhibitors in melanoma cells: Prodigiosin vs. obatoclax
M. Espona-Fiedler et al.
BIOCHEMICAL PHARMACOLOGY (2012)
Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State
Isabel Garcia-Cao et al.
CELL (2012)
Genetic alterations of PTEN in human melanoma
Almass-Houd Aguissa-Toure et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Transcriptomic Analysis of Mouse Embryonic Skin Cells Reveals Previously Unreported Genes Expressed in Melanoblasts
Sophie Colombo et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing
Bojana Djordjeyic et al.
MODERN PATHOLOGY (2012)
Combinations of BRAF, MEK, and PI3K/mTOR Inhibitors Overcome Acquired Resistance to the BRAF Inhibitor GSK2118436 Dabrafenib, Mediated by NRAS or MEK Mutations
James G. Greger et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma
Sergey I. Nikolaev et al.
NATURE GENETICS (2012)
Genomic characterisation of acral melanoma cell lines
Simon J. Furney et al.
PIGMENT CELL & MELANOMA RESEARCH (2012)
Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition
W. Deng et al.
PIGMENT CELL & MELANOMA RESEARCH (2012)
Lhermitte-Duclos Disease Presenting with Hydrocephalus
Mun Sul Yang et al.
HYDROCEPHALUS (2012)
New Therapeutic Targets in Melanoma
R. M. Marti et al.
ACTAS DERMO-SIFILIOGRAFICAS (2012)
Novice Identification of Melanoma: Not Quite as Straightforward as the ABCDs
R. Benjamin Aldridge et al.
ACTA DERMATO-VENEREOLOGICA (2011)
Modèles murins de mélanomes cutanés. Importance du fond génétique
Christine Longvert et al.
ANNALES DE PATHOLOGIE (2011)
Melanomas Detected in a Follow-up Program Compared With Melanomas Referred to a Melanoma Unit
Gabriel Salerni et al.
ARCHIVES OF DERMATOLOGY (2011)
β-Catenin Signaling Controls Metastasis in Braf-Activated Pten-Deficient Melanomas
William E. Damsky et al.
CANCER CELL (2011)
PTEN Loss Confers BRAF Inhibitor Resistance to Melanoma Cells through the Suppression of BIM Expression
Kim H. T. Paraiso et al.
CANCER RESEARCH (2011)
Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner
Min Sup Song et al.
CELL (2011)
In Vivo Identification of Tumor-Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma
Florian A. Karreth et al.
CELL (2011)
Acral Lentiginous Melanoma
Melissa Peck Piliang
CLINICS IN LABORATORY MEDICINE (2011)
Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling
Nikhil Wagle et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Key points in the dermoscopic diagnosis of hypomelanotic melanoma and nodular melanoma
Fergal J. Moloney et al.
JOURNAL OF DERMATOLOGY (2011)
Asymmetric PI(3,4,5)P3 and Akt Signaling Mediates Chemotaxis of Axonal Growth Cones
Steven J. Henle et al.
JOURNAL OF NEUROSCIENCE (2011)
Anti-CTLA-4 antibodies A major therapeutic advance in metastatic melanoma treatment
Caroline Robert et al.
M S-MEDECINE SCIENCES (2011)
Reversing Melanoma Cross-Resistance to BRAF and MEK Inhibitors by Co-Targeting the AKT/mTOR Pathway
Mohammad Atefi et al.
PLOS ONE (2011)
The Evolution of Melanoma Diagnosis: 25 Years Beyond the ABCDs
Darrell S. Rigel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2010)
Rapamycin inhibits lung metastasis of B16 melanoma cells through down-regulating alphav integrin expression and up-regulating apoptosis signaling
Zhuoshun Yang et al.
CANCER SCIENCE (2010)
Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF
Sonja J. Heidorn et al.
CELL (2010)
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
Laura Poliseno et al.
NATURE (2010)
Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis
C. Nogueira et al.
ONCOGENE (2010)
Deletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction
Isabel Puig et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
BrafV600E cooperates with Pten loss to induce metastatic melanoma
David Dankort et al.
NATURE GENETICS (2009)
A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN
Meghdad Rahdar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis
Tae Inoue-Narita et al.
CANCER RESEARCH (2008)
Tenets of PTEN tumor suppression
Leonardo Salmena et al.
CELL (2008)
Melanomagenesis - Overcoming the barrier of melanocyte senescence
Linan Ha et al.
CELL CYCLE (2008)
The nuclear affairs of PTEN
Sarah M. Planchon et al.
JOURNAL OF CELL SCIENCE (2008)
The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey
C. B. Knobbe et al.
ONCOGENE (2008)
The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization
Fatemeh Fouladkou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cutaneous melanoma in genetically modified animals
Lionel Larue et al.
PIGMENT CELL RESEARCH (2007)
β-Catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development
Veronique Delmas et al.
GENES & DEVELOPMENT (2007)
Rare cancer-specific mutations in PIK3CA show gain of function
Marco Gymnopoulos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Essential role for nuclear PTEN in maintaining chromosomal integrity
Wen Hong Shen et al.
CELL (2007)
Ubiquitination regulates PTEN nuclear import and tumor suppression
Lloyd C. Trotman et al.
CELL (2007)
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
Xinjiang Wang et al.
CELL (2007)
Protein expression and cellular localization in two prognostic subgroups of diffuse large B-cell lymphoma: Higher expression of ZAP70 and PKC-beta II in the non-germinal center group and poor survival in patients deficient in nuclear PTEN
Marie Fridberg et al.
LEUKEMIA & LYMPHOMA (2007)
A conserved transcriptional enhancer that specifies Tyrp1 expression to melanocytes
Fabien Murisier et al.
DEVELOPMENTAL BIOLOGY (2006)
PCAF modulates PTEN activity
Koichi Okumura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation
Ji-Hyun Chung et al.
HUMAN MOLECULAR GENETICS (2006)
Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
V. C. Gray-Schopfer et al.
BRITISH JOURNAL OF CANCER (2006)
Characterization of melanocyte-specific inducible Cre recombinase transgenic mice
M Bosenberg et al.
GENESIS (2006)
Presentation and detection of invasive melanoma in a high-risk population
M McPherson et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2006)
Variation in incidence and fatality of melanoma by season of diagnosis in New South Wales, Australia
M Boniol et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2006)
Spatiotemporal gene control by the Cre-ERT2 system in melanocytes
I Yajima et al.
GENESIS (2006)
mTOR•RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes
RC Hresko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Epithelial-mesenchymal transition in development and cancer:: role of phosphatidylinositol 3′ kinase/AKT pathways
L Larue et al.
ONCOGENE (2005)
Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3β
AM Al-Khouri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Increased protein expression of the PTEN tumor suppressor in the presence of constitutively active Notch-1
WH Chappell et al.
CELL CYCLE (2005)
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
ZB Chen et al.
NATURE (2005)
BRAFE600-associated senescence-like cell cycle arrest of human naevi
C Michaloglou et al.
NATURE (2005)
Metastasizing melanoma formation caused by expression of activated N-RasQ61K on an INK4a-deficient background
J Ackermann et al.
CANCER RESEARCH (2005)
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov et al.
SCIENCE (2005)
High frequency of mutations of the PIK3CA gene in human cancers
Y Samuels et al.
SCIENCE (2004)
Melanocytes and pigmentation are affected in dopachrome tautomerase knockout mice
L Guyonneau et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors
J Kwon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Redox regulation of PI 3-kinase signalling via inactivation of PTEN
NR Leslie et al.
EMBO JOURNAL (2003)
Malignant melanoma in South Africans of mixed ancestry: a retrospective analysis
MC Swan et al.
MELANOMA RESEARCH (2003)
Cre-mediated recombination in the skin melanocyte lineage
V Delmas et al.
GENESIS (2003)
Genetics of melanoma predisposition
NK Hayward
ONCOGENE (2003)
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms
DJ Freeman et al.
CANCER CELL (2003)
Tyrosinase-Cre mice for tissue-specific gene ablation in neural crest and neuroepithelial-derived tissues
ID Tonks et al.
GENESIS (2003)
Direct identification of PTEN phosphorylation sites
SJ Miller et al.
FEBS LETTERS (2002)
PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers
XP Zhou et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Reversible inactivation of the tumor suppressor PTEN by H2O2
SR Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma
DC Whiteman et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice
MJ You et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Melanoma in African-Americans: Trends in biological behavior and clinical characteristics over two decades
CF Bellows et al.
JOURNAL OF SURGICAL ONCOLOGY (2001)
Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production
D Kim et al.
FASEB JOURNAL (2001)
PTEN/MMAC1 in malignant melanoma and its importance for tumor progression
M Poetsch et al.
CANCER GENETICS AND CYTOGENETICS (2001)
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus - Implications for PTEN stability to proteasome-mediated degradation
J Torres et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells
A Perren et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2
XY Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Allelic losses on chromosome arm 10q and mutation of the PTEN (MMAC1) tumour suppressor gene in primary and metastatic malignant melanomas
J Reifenberger et al.
VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY (2000)
分享论文
