相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant
Thomas Frogne et al.
BREAST CANCER RESEARCH AND TREATMENT (2009)
Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941
Teemu T. Junttila et al.
CANCER CELL (2009)
Gene Expression Profiling of ErbB Receptors and Ligands in Human Meningiomas
Ingrid Laurendeau et al.
CANCER INVESTIGATION (2009)
Analysis of ErbB Receptors in Pulmonary Carcinoid Tumors
Otis B. Rickman et al.
CLINICAL CANCER RESEARCH (2009)
Interaction of antibodies with ErbB receptor extracellular regions
Karl R. Schmitz et al.
EXPERIMENTAL CELL RESEARCH (2009)
Nedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cells
Fenghua Zeng et al.
FASEB JOURNAL (2009)
The ErbB4 Growth Factor Receptor Is Required for Colon Epithelial Cell Survival in the Presence of TNF
Mark R. Frey et al.
GASTROENTEROLOGY (2009)
ErbB family immunohistochemical expression in colorectal cancer patients with higher risk of recurrence after radical surgery
Glauco Baiocchi et al.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2009)
Somatic Mutations of ErbB4 SELECTIVE LOSS-OF-FUNCTION PHENOTYPE AFFECTING SIGNAL TRANSDUCTION PATHWAYS IN CANCER
Denis Tvorogov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium
Daekee Lee et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Value and Limitations of Measuring HER-2 Extracellular Domain in the Serum of Breast Cancer Patients
Alexandra F. Leary et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
The E3 Ubiquitin Ligase WWP1 Selectively Targets HER4 and Its Proteolytically Derived Signaling Isoforms for Degradation
Shu-Mang Feng et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
ErbB4 Splice Variants Cyt1 and Cyt2 Differ by 16 Amino Acids and Exert Opposing Effects on the Mammary Epithelium In Vivo
Rebecca S. Muraoka-Cook et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4
Todd D. Prickett et al.
NATURE GENETICS (2009)
Somatic EGFR mutations and efficacy of tyrosine kinase inhibitors in NSCLC
Helena Linardou et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2009)
Real-time quantitative polymerase chain reaction (qPCR) analysis with fluorescence resonance energy transfer (FRET) probes reveals differential expression of the four ERBB4 juxtamembrane region variants between medulloblastoma and pilocytic astrocytoma
N. Zeng et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2009)
Suppression of breast cancer cell growth by a monoclonal antibody targeting cleavable ErbB4 isoforms
M. Hollmen et al.
ONCOGENE (2009)
Mutated ERBB4: a novel drug target in metastatic melanoma?
Kari Kurppa et al.
PIGMENT CELL & MELANOMA RESEARCH (2009)
Expression of tumor necrosis factor α converting enzyme in endocrine cancers
Tove Kirkegaard et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2008)
Clinical utility of type 1 growth factor receptor expression in colon cancer
Sher-Ping Leung et al.
AMERICAN JOURNAL OF SURGERY (2008)
Evaluation of type 1 growth factor receptor family expression in benign and malignant thyroid lesions
Sam M. Wiseman et al.
AMERICAN JOURNAL OF SURGERY (2008)
Novel human antibody therapeutics: The age of the Umabs
Sigrid R. Ruuls et al.
Biotechnology Journal (2008)
Evaluation of the prognostic and predictive value of HER family mRNA expression in high-risk early breast cancer: A Hellenic Cooperative Oncology Group (HeCOG) study
A. K. Koutras et al.
BRITISH JOURNAL OF CANCER (2008)
Anti-ERBb4 targeted therapy combined with radiation therapy in prostate cancer - Results of in vitro and invivo studies
Akiva Vexler et al.
CANCER BIOLOGY & THERAPY (2008)
Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization
Judith Schmiedel et al.
CANCER CELL (2008)
The HER4/4ICD estrogen receptor coactivator and BH3-only protein is an effector of tamoxifen-induced apoptosis
Anjali Naresh et al.
CANCER RESEARCH (2008)
The epidermal growth factor receptor family: Biology driving targeted therapeutics
M. J. Wieduwilt et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Panitumumab: Human monoclonal antibody against epidermal growth factor receptors for the treatment of metastatic colorectal cancer
Mel Wu et al.
CLINICAL THERAPEUTICS (2008)
ErbB4/HER4: Role in mammary gland development, differentiation and growth inhibition
Rebecca S. Muraoka-Cook et al.
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2008)
HER4 intracellular domain (4ICD) activity in the developing mammary gland and breast cancer
Frank E. Jones
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2008)
The role of ErbB3 and its binding partners in breast cancer progression and resistance to hormone and tyrosine kinase directed therapies
Anne W. Hamburger
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2008)
Role of ErbB4 in breast cancer
Maria Sundvall et al.
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2008)
Distinctive expression pattern of ErbB family receptors signifies an aggressive variant of bladder cancer
Wassim Kassouf et al.
JOURNAL OF UROLOGY (2008)
Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab
Shizhen Emily Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Somatic mutations affect key pathways in lung adenocarcinoma
Li Ding et al.
NATURE (2008)
ERBB receptors in developing, dysplastic and malignant oral epithelia
J. Rautava et al.
ORAL ONCOLOGY (2008)
被撤回的出版物: The antibody zalutumumab inhibits epidermal growth factor receptor signaling by limiting intra- and intermolecular flexibility (Retracted article. See vol. 109, pg. 5548, 2012)
Jeroen J. Larnmerts van Bueren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms
Maria Sundvall et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Nuclear translocation of HER-4/c-erbB-4 is significantly correlated with prognosis of Esophageal squamous cell carcinoma
Shuangta Xu et al.
JOURNAL OF SURGICAL ONCOLOGY (2008)
Cytogenetic analysis of HER1/EGFR, HER2, HER3 and HER4 in 278 breast cancer patients
Andrea Sassen et al.
BREAST CANCER RESEARCH (2008)
A novel polymorphism in the promoter region of ERBB4 is associated with breast and colorectal cancer risk
Matjaz Rokavec et al.
CLINICAL CANCER RESEARCH (2007)
Erb4 isofors selectively regulate growth factor-induced adin-darby canine kidney cell tubulogenesis
Fenghua Zeng et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Wwox and Ap2γ expression levels predict tamoxifen response
Gulnur Guler et al.
CLINICAL CANCER RESEARCH (2007)
Phase I/II clinical and pharmacokinetic study evaluating a fully human monoclonal antibody against EGFr (HuMax-EGFr) in patients with advanced squamous cell carcinoma of the head and neck
Lars Bastholt et al.
RADIOTHERAPY AND ONCOLOGY (2007)
Association of Wwox with ErbB4 in breast cancer
Rami I. Aqeilian et al.
CANCER RESEARCH (2007)
From XenoMouse technology to panitumumab, the first fully human antibody product from transgenic mice
Aya Jakobovits et al.
NATURE BIOTECHNOLOGY (2007)
The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation
Jasminka Omerovic et al.
FASEB JOURNAL (2007)
The HER4 cytoplasmic domain, but not its c terminus, inhibits mammary cell proliferation
Shu-Mang Feng et al.
MOLECULAR ENDOCRINOLOGY (2007)
ErbB4 expression and mutation in Japanese patients with lung cancer
Hidefumi Sasaki et al.
CLINICAL LUNG CANCER (2007)
E-cadherin cell-cell adhesion in Ewing tumor cells mediates suppression of anoikis through activation of the ErbB4 tyrosine kinase
Hyung-Gyoo Kang et al.
CANCER RESEARCH (2007)
Targeting EGF-receptor-signalling in squamous cell carcinomas of the head and neck
C. W. M. Reuter et al.
BRITISH JOURNAL OF CANCER (2007)
Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia
Amanda J. Law et al.
HUMAN MOLECULAR GENETICS (2007)
Expression of the epidermal growth factor system in endometrioid endometrial cancer
Kirsten Ejskjaer et al.
GYNECOLOGIC ONCOLOGY (2007)
A constitutively active ERBB4/HER4 allele with enhanced transcriptional coactivation and cell-killing activities
G. A. Vidal et al.
ONCOGENE (2007)
A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study
Joanne M. Murabito et al.
BMC MEDICAL GENETICS (2007)
Panitumumab the first fully human monoclonal antibody: from the bench to the clinic
Michael Cohenuram et al.
ANTI-CANCER DRUGS (2007)
ErbB receptors: new insights on mechanisms and biology
Bryan Linggi et al.
TRENDS IN CELL BIOLOGY (2006)
Alternative splicing of the ErbB-4 cytoplasmic domain and its regulation by hedgehog signaling identify distinct medulloblastoma subsets
E. Ferretti et al.
ONCOGENE (2006)
Phosphorylation of ErbB4 on Tyr1056 is critical for inhibition of colony formation by prostate tumor cell lines
Richard M. Gallo et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain
S. Pablo Sardi et al.
CELL (2006)
Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4
A. J. Jackson-Fisher et al.
ONCOGENE (2006)
The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells
Rebecca S. Muraoka-Cook et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
ErbB-4s80 intracellular domain abrogates ETO2-dependent transcriptional repression
Bryan Linggi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Coregulation of estrogen receptor by ERBB4/HER4 establishes a growth-promoting autocrine signal in breast tumor cells
Yun Zhu et al.
CANCER RESEARCH (2006)
ErbB4 increases the proliferation potential of human lung cancer cells and its blockage can be used as a target for anti-cancer therapy
Alex Starr et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Signaling through ERBB receptors: Multiple layers of diversity and control
CM Warren et al.
CELLULAR SIGNALLING (2006)
The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells
Anjali Naresh et al.
CANCER RESEARCH (2006)
Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells
Phillip C. C. Liu et al.
CANCER BIOLOGY & THERAPY (2006)
Somatic mutations of the ERBB4 kinase domain in human cancers
YH Soung et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Gene expression profiling of ERBB receptors and ligands in human transitional cell carcinoma of the bladder
D Amsellem-Ouazana et al.
JOURNAL OF UROLOGY (2006)
Prognostic significance of HER3 and HER4 protein expression in colorectal adenocarcinomas
P Kountourakis et al.
BMC CANCER (2006)
Heregulin-dependent delay in mitotic progression requires HER4 and BRCA1
Rebecca S. Muraoka-Cook et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth
JA Maatta et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
HER4 in breast cancer: comparison of antibodies against intra- and extra-cellular domains of HER4
SM Tovey et al.
BREAST CANCER RESEARCH (2006)
Secretase-dependent tyrosine phosphorylation of Mdm2 by the ErbB-4 intracellular domain fragment
RR Arasada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function
RI Aqeilan et al.
CANCER RESEARCH (2005)
ERBB receptors and cancer: The complexity of targeted inhibitors
NE Hynes et al.
NATURE REVIEWS CANCER (2005)
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
SQ Li et al.
CANCER CELL (2005)
Absence of HER4 expression predicts recurrence of ductal carcinoma in situ of the breast
NLP Barnes et al.
CLINICAL CANCER RESEARCH (2005)
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
W Pao et al.
PLOS MEDICINE (2005)
Cleavable ErbB4 isoform in estrogen receptor-regulated growth of breast cancer cells
TT Junttila et al.
CANCER RESEARCH (2005)
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
MC Franklin et al.
CANCER CELL (2004)
Expression of HER3, HER4 and their ligand heregulin-4 is associated with better survival in bladder cancer patients
AA Memon et al.
BRITISH JOURNAL OF CANCER (2004)
The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone
CC Williams et al.
JOURNAL OF CELL BIOLOGY (2004)
EGFR mutations in lung cancer:: Correlation with clinical response to gefitinib therapy
JG Paez et al.
SCIENCE (2004)
Frequent overexpression of multiple ErbB receptors by head and neck squamous cell carcinoma contrasts with rare antibody immunity in patients
R Bei et al.
JOURNAL OF PATHOLOGY (2004)
Expression and co-expression of the members of the epidermal growth factor receptor (EGFR) family in invasive breast carcinoma
DM Abd El-Rehim et al.
BRITISH JOURNAL OF CANCER (2004)
Dual mode of action of a human anti-epidermal growth factor receptor monoclonal antibody for cancer therapy
WK Bleeker et al.
JOURNAL OF IMMUNOLOGY (2004)
Ectodomain cleavage of ErbB-4 - Characterization of the cleavage site and m80 fragment
QC Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Prognostic value of ERBB family mRNA expression in breast carcinomas
I Bièche et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors
AW Burgess et al.
MOLECULAR CELL (2003)
WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
A Komuro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Expression of the HERI-4 family of receptor tyrosine kinases in breast cancer
CJ Witton et al.
JOURNAL OF PATHOLOGY (2003)
Type 1 growth factor receptor expression in node positive breast cancer: adverse prognostic significance of c-erbB-4
AJ Lodge et al.
JOURNAL OF CLINICAL PATHOLOGY (2003)
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
HS Cho et al.
NATURE (2003)
The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors
TPJ Garrett et al.
MOLECULAR CELL (2003)
Neuregulin-1 and ErbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease
AR Chaudhury et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)
Antiproliferative, antiangiogenic and proapoptotic activity of h-R3:: A humanized anti-EGFR antibody
T Crombet-Ramos et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
ErbB-4 expression in limb soft-tissue sarcoma: correlation with the results of neoadjuvant chemotherapy
O Merimsky et al.
EUROPEAN JOURNAL OF CANCER (2002)
Investigation of the prognostic value of coexpressed erbB family members for the survival of colorectal cancer patients after curative surgery
JC Lee et al.
EUROPEAN JOURNAL OF CANCER (2002)
Presenilin-dependent γ-secretase-like intramembrane cleavage of ErbB4
HJ Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival
Z Suo et al.
JOURNAL OF PATHOLOGY (2002)
γ-Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase
CY Ni et al.
SCIENCE (2001)
Correlation between c-erbB-4 receptor expression and response to gemcitabine-cisplatin chemotherapy in non-small-cell lung cancer
O Merimsky et al.
ANNALS OF ONCOLOGY (2001)
HER4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells
CI Sartor et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Tumor necrosis factor-α-converting enzyme is required for cleavage of erbB4/HER4
C Rio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis
V Kainulainen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
c-erbB-4 protein expression in human breast cancer
TY Kew et al.
BRITISH JOURNAL OF CANCER (2000)