期刊
FUTURE MEDICINAL CHEMISTRY
卷 5, 期 6, 页码 693-704出版社
FUTURE SCI LTD
DOI: 10.4155/FMC.13.39
关键词
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资金
- US Department of Energy
- Robert H Cole Foundation
The treatment of cancer remains one of the most challenging problems for humanity. Boron neutron capture therapy is a binary approach for cancer treatment that is particularly attractive in treating high-grade gliomas and metastatic brain tumors. Among the types of boron-containing molecules used as boron neutron capture therapy agents, boronated carbohydrate derivatives have received significant attention because of their preferential uptake by growing tumor cells. This review provides a summary of the recent developments in the chemistry of carborane-containing carbohydrates.
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