相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Enhanced Phosphatase Activity Attenuates α-Synucleinopathy in a Mouse Model
Kang-Woo Lee et al.
JOURNAL OF NEUROSCIENCE (2011)
Open-label, phase I dose-escalation study of sodium selenate, a novel activator of PP2A, in patients with castration-resistant prostate cancer
N. M. Corcoran et al.
BRITISH JOURNAL OF CANCER (2010)
Nutritional status of selenium in Alzheimer's disease patients
Barbara Rita Cardoso et al.
BRITISH JOURNAL OF NUTRITION (2010)
Vitamin E Forms in Alzheimer's Disease: A Review of Controversial and Clinical Experiences
Owoedimo B. Usoro et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2010)
The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment
Xiaochuan Wang et al.
FASEB JOURNAL (2010)
Sphingosine Interaction with Acidic Leucine-rich Nuclear Phosphoprotein-32A (ANP32A) Regulates PP2A Activity and Cyclooxygenase (COX)-2 Expression in Human Endothelial Cells
Cheryl Habrukowich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Phosphorylation of Tau at Thr212, Thr231, and Ser262 Combined Causes Neurodegeneration
Alejandra D. Alonso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Progesterone decreases tyrosine hydroxylase phosphorylation state and increases protein phosphatase 2A activity in the stalk-median eminence on proestrous afternoon
Bin Liu et al.
JOURNAL OF ENDOCRINOLOGY (2010)
Discovery of Brain-Penetrant, Orally Bioavailable Aminothienopyridazine Inhibitors of Tau Aggregation
Carlo Ballatore et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Synthesis, Inhibitory Activity of Cholinesterases, and Neuroprotective Profile of Novel 1,8-Naphthyridine Derivatives
Cristobal de los Rios et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Inhibition of c-Jun kinase provides neuroprotection in a model of Alzheimer's disease
Steven P. Braithwaite et al.
NEUROBIOLOGY OF DISEASE (2010)
Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models
Janet van Eersel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Development of Tau Aggregation Inhibitors for Alzheimer's Disease
Bruno Bulic et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Taurolidine and oxidative stress: a rationale for local treatment of mesothelioma
N. Aceto et al.
EUROPEAN RESPIRATORY JOURNAL (2009)
Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling
Archana Mukhopadhyay et al.
FASEB JOURNAL (2009)
Structure-Activity Relationship of Cyanine Tau Aggregation Inhibitors
Edward Chang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Activation of p38 Mitogen-Activated Protein Kinase Is Required for Death Receptor-Independent Caspase-8 Activation and Cell Death in Response to Sphingosine
Chang-Hwan Yoon et al.
MOLECULAR CANCER RESEARCH (2009)
JNK regulates APP cleavage and degradation in a model of Alzheimer's disease
Alessio Colombo et al.
NEUROBIOLOGY OF DISEASE (2009)
Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity
C. H. Switzer et al.
ONCOGENE (2009)
Cdc25B Phosphatase Inhibitors in Cancer Therapy: Latest Developments, Trends and Medicinal Chemistry Perspective
Antonio Lavecchia et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2008)
Protein phosphatase 2A (PP2A), a drugable tumor suppressor in Ph1(+) leukemias
Danilo Perrotti et al.
CANCER AND METASTASIS REVIEWS (2008)
Structural mechanism of demethylation and inactivation of protein phosphatase 2A
Yongna Xing et al.
CELL (2008)
Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A
Xin-Wen Zhou et al.
NEUROBIOLOGY OF DISEASE (2008)
Linking Aβ and Tau in Late-Onset Alzheimer's Disease: A Dual Pathway Hypothesis
Scott A. Small et al.
NEURON (2008)
Tau-based treatment strategies in neurodegenerative diseases
Anja Schneider et al.
NEUROTHERAPEUTICS (2008)
FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma
Qing Liu et al.
BLOOD (2008)
Beyond amyloid: The next generation of Alzheimer's disease therapeutics
Guy R. Seabrook et al.
MOLECULAR INTERVENTIONS (2007)
Looking for novel ways to treat the hallmarks of Alzheimer's disease
Alistair J. Stewart et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2007)
Untangling tau hyperphosphorylation in drug design for neurodegenerative diseases
Michael P. Mazanetz et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40
Yu Chen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Disruption of microtubule network by Alzheimer abnormally hyperphosphorylated tau
Bin Li et al.
ACTA NEUROPATHOLOGICA (2007)
被撤回的出版物: Activation of protein phosphatase 2A by palmitate inhibits AMP-activated protein kinase (Retracted article. See vol. 294, pg. 10741, 2019)
Yong Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice
Kevin H. J. Park et al.
JOURNAL OF NEUROSCIENCE (2007)
Plasma selenium over time and cognitive decline in the elderly
N. Tasnime Akbaraly et al.
EPIDEMIOLOGY (2007)
Rhodanine-based tau aggregation inhibitors in cell models of tauopathy
Bruno Bulic et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)
Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration
Jian-Zhi Wang et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Microtubule-associated protein tau as a therapeutic target in neurodegenerative disease
Hanno M. Roder et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2007)
Mitotic phosphatases: no longer silent partners
Laura Trinkle-Mulcahy et al.
CURRENT OPINION IN CELL BIOLOGY (2006)
Current strategies for the treatment of Alzheimer's disease and other tauopathies
Chad A. Dickey et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2006)
Dihydroxyphenylethanol induces apoptosis by activating serine/threonine protein phosphatase PP2A and promotes the endoplasmic reticulum stress response in human colon carcinoma cells
Cecile Guichard et al.
CARCINOGENESIS (2006)
Troglitazone acutely inhibits protein synthesis in endothelial cells via a novel mechanism involving protein phosphatase 2A-dependent p70 S6 kinase inhibition
Du-Hyong Cho et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Lithium inhibits ceramide-and etoposide-induced protein phosphatase 2A methylation, Bcl-2 dephosphorylation, caspase-2 activation, and apoptosis
Chia-Ling Chen et al.
MOLECULAR PHARMACOLOGY (2006)
Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine
Muhammad Omar Chohan et al.
FEBS LETTERS (2006)
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein
P Neviani et al.
CANCER CELL (2005)
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
F Liu et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease
H Tanimukai et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Inhibitors of protein phosphatase-2A from human brain structures, immunocytological localization and activities towards dephosphorylation of the Alzheimer type hyperphosphorylated tau
I Tsujio et al.
FEBS LETTERS (2005)
Altered expression levels of the protein phosphatase 2A ABαC enzyme are associated with Alzheimer disease pathology
E Sontag et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
The structural requirements for ceramide activation of serine-threonine protein phosphatases
CE Chalfant et al.
JOURNAL OF LIPID RESEARCH (2004)
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease
RG Cutler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
MARKing tau for tangles and toxicity
G Drewes
TRENDS IN BIOCHEMICAL SCIENCES (2004)
Mitogen-activated protein kinases and the evolution of Alzheimer's: a revolutionary neurogenetic axis for therapeutic intervention?
JJ Haddad
PROGRESS IN NEUROBIOLOGY (2004)
Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis
E Sontag et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
APP processing is regulated by cytoplasmic phosphorylation
MS Lee et al.
JOURNAL OF CELL BIOLOGY (2003)
Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal
W Liu et al.
CELL DEATH AND DIFFERENTIATION (2003)
A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells
Y Matsuoka et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Inhibition of protein phosphatase 2A- and protein phosphatase 1-induced tau hyperphosphorylation and impairment of spatial memory retention in rats
L Sun et al.
NEUROSCIENCE (2003)
Selenium intake, mood and other aspects of psychological functioning
D Benton
NUTRITIONAL NEUROSCIENCE (2002)
Role of serine/threonine protein phosphatase in Alzheimer's disease
Q Tian et al.
NEUROSIGNALS (2002)
A functional role for the B56 α-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function
PP Ruvolo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Computational approaches to the prediction of the blood-brain distribution
U Norinder et al.
ADVANCED DRUG DELIVERY REVIEWS (2002)
Serine-threonine protein phosphatase inhibitors: Development of potential therapeutic strategies
A McCluskey et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments
AD Alonso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus
V Vogelsberg-Ragaglia et al.
EXPERIMENTAL NEUROLOGY (2001)
Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo
J Wu et al.
EMBO JOURNAL (2000)
Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits
T Tolstykh et al.
EMBO JOURNAL (2000)
分享论文
