期刊
FRONTIERS IN HUMAN NEUROSCIENCE
卷 7, 期 -, 页码 -出版社
FRONTIERS RESEARCH FOUNDATION
DOI: 10.3389/fnhum.2013.00155
关键词
TMS; EEG; state space; brain dynamics; trajectory; recurrence quantification analysis
资金
- Academy of Finland
To improve our understanding of the combined transcranial magnetic stimulation (TMS) and electroencephalography (EEG) method in general, it is important to study how the dynamics of the TMS-modulated brain activity differs from the dynamic of spontaneous activity. In this paper, we introduce two quantitative measures based on EEG data, called mean state shift (MSS) and state variance (SV), for evaluating the TMS-evoked changes in the brain-state dynamics. MSS quantifies the immediate TMS-elicited change in the brain state, whereas SV shows whether the rate at which the brain state changes is modulated by TMS. We report a statistically significant increase for a period of 100-200 ms after the TMS pulse in both MSS and SV at the group level. This indicates that the TMS-modulated brain state differs from the spontaneous one. Moreover, the TMS-modulated activity is more vigorous than the natural activity.
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