期刊
FRONTIERS IN BIOSCIENCE-LANDMARK
卷 13, 期 -, 页码 1281-1293出版社
FRONTIERS IN BIOSCIENCE INC
DOI: 10.2741/2761
关键词
tomography; bioluminescence; imaging; review
资金
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R33EB001685, R01EB002667, R21EB001685, R21EB000830, R33EB000830] Funding Source: NIH RePORTER
- NIBIB NIH HHS [EB000830, EB002667, EB001685] Funding Source: Medline
According to the NIH roadmap (1), optical molecular imaging has an instrumental role in the development of molecular medicine. Great efforts, including those with bioluminescent imaging techniques, have been made to understand the linkage between genes and phenotypic expressions in normal and disease biology. Currently, bioluminescent techniques are widely used in small animal studies. However, most of the current bioluminescent imaging techniques are done in the 2D mode. In this overview, we review bioluminescence tomography (3D mode), elaborate on its principle and multi-spectral extension, describe associated image unmixing and normalization techniques, and discuss a number of directions for technical improvements and biomedical applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据