相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Ceramide and Apoptosis: Exploring the Enigmatic Connections between Sphingolipid Metabolism and Programmed Cell Death
Thomas D. Mullen et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2012)
Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases
Daniel Canals et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics
Jean-Claude Martinou et al.
DEVELOPMENTAL CELL (2011)
Role of protein kinase C and mitochondrial permeability transition pore in the neuroprotective effect of ceramide in ischemia-induced cell death
Alba Agudo-Lopez et al.
FEBS LETTERS (2011)
Neuroprotective mechanisms of minocycline against sphingomyelinase/ceramide toxicity: Roles of Bcl-2 and thioredoxin
Ching-Min Tang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Neuroprotection by Minocycline Caused by Direct and Specific Scavenging of Peroxynitrite
Stefan Schildknecht et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Minocycline Prevents Morphine-Induced Apoptosis in Rat Cerebral Cortex and Lumbar Spinal Cord: A Possible Mechanism for Attenuating Morphine Tolerance
Kambiz Hassanzadeh et al.
NEUROTOXICITY RESEARCH (2011)
Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature
Michael O. Griffin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)
Prospects for Minocycline Neuroprotection
Jennifer M. Plane et al.
ARCHIVES OF NEUROLOGY (2010)
Mitochondrial mechanisms in amyloid beta peptide-induced cerebrovascular degeneration
Ming-Jen Hsu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2010)
Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis
Norman J. Haughey et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
Minocycline is cytoprotective in human corneal endothelial cells and induces anti-apoptotic B-cell CLL/lymphoma 2 (Bcl-2) and X-linked inhibitor of apoptosis (XIAP)
Marcus Kernt et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2010)
The Acid Sphingomyelinase/Ceramide Pathway: Biomedical Significance and Mechanisms of Regulation
Y. H. Zeidan et al.
CURRENT MOLECULAR MEDICINE (2010)
Reductions in Amyloid-beta-Derived Neuroinflammation, with Minocycline, Restore Cognition but do not Significantly Affect Tau Hyperphosphorylation
Anna Parachikova et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Deregulated Sphingolipid Metabolism and Membrane Organization in Neurodegenerative Disorders
Marco Piccinini et al.
MOLECULAR NEUROBIOLOGY (2010)
Mammalian Neutral Sphingomyelinases: Regulation and Roles in Cell Signaling Responses
Bill X. Wu et al.
NEUROMOLECULAR MEDICINE (2010)
The Role of Mitochondria in Apoptosis
Chunxin Wang et al.
ANNUAL REVIEW OF GENETICS (2009)
Minocycline and neurodegenerative diseases
Hye-Sun Kim et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke
Noriyuki Matsukawa et al.
BMC NEUROSCIENCE (2009)
Regulation of ceramide-induced neuronal death: Cell metabolism meets neurodegeneration
Gonzalo Arboleda et al.
BRAIN RESEARCH REVIEWS (2009)
Ceramide and Mitochondria in Ischemia/Reperfusion
Sergei A. Noygorodov et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2009)
Ceramide and neurodegeneration: Susceptibility of neurons and oligodendrocytes to cell damage and death
Arundhati Jana et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2009)
Antioxidant potential of Minocycline in Japanese Encephalitis Virus infection in murine neuroblastoma cells: Correlation with membrane fluidity and cell death
Manoj Kumar Mishra et al.
NEUROCHEMISTRY INTERNATIONAL (2009)
Neuroprotective role of minocycline in co-cultures of human fetal neurons and microglia
Radmila Fillpovic et al.
EXPERIMENTAL NEUROLOGY (2008)
Minocycline protects Schwann cells from ischemia-like injury and promotes axonal outgrowth in bioartificial nerve grafts lacking Wallerian degeneration
Gerburg Keilhoff et al.
EXPERIMENTAL NEUROLOGY (2008)
Emerging pathways in genetic Parkinson's disease: Potential role of ceramide metabolism in Lewy body disease
Jose Bras et al.
FEBS JOURNAL (2008)
Multifaceted roles of sphingosine-1-phosphate: How does this bioactive sphingolipid fit with acute neurological injury?
Indrapal N. Singh et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Lipid signalling in disease
Matthias P. Wymann et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Principles of bioactive lipid signalling: lessons from sphingolipids
Yusuf A. Hannun et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Minocycline provides protection against β-amyloid(25-35)-induced alterations of the somatostatin signaling pathway in the rat temporal cortex
E. Burgos-Ramos et al.
NEUROSCIENCE (2008)
Exploiting endogenous anti-apoptotic proteins for novel therapeutic strategies in cerebral ischemia
Abdelhaq Rami et al.
PROGRESS IN NEUROBIOLOGY (2008)
Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C-elegans
Xinzhu Deng et al.
SCIENCE (2008)
Ceramide synthesis in the endoplasmic reticulum can permeabilize mitochondria to proapoptotic proteins
Johnny Stiban et al.
JOURNAL OF LIPID RESEARCH (2008)
Monitoring the protective effects of minocycline treatment with radiolabeled annexin v in an experimental model of focal cerebral ischemia
Man Nan Tang et al.
JOURNAL OF NUCLEAR MEDICINE (2007)
Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's Disease models
Yoori Choi et al.
NEUROPSYCHOPHARMACOLOGY (2007)
JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction
Jin Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mechanism of inhibition of sequestration of protein kinase C α/βII by ceramide -: Roles of ceramide-activated protein phosphatases and phosphorylation/dephosphorylation of protein kinase C α/βII on threonine 638/641
Kazuyuki Kitatani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Ceramide recruits and activates protein kinase C ζ (PKCζ) within structured membrane microdomains
Todd E. Fox et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Minocycline reduces microglial activation and improves behavioral deficits in a transgenic model of cerebral microvascular amyloid
Rong Fan et al.
JOURNAL OF NEUROSCIENCE (2007)
Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy
Wenjing Zheng et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)
A house divided: Ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death
Tarek A. Taha et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)
Sphingolipids in apoptosis, survival and regeneration in the nervous system
Elena I. Posse de Chaves
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)
TRAIL activates acid sphingomyelinase via a redox mechanism and releases ceramide to trigger apoptosis
C. A. Dumitru et al.
ONCOGENE (2006)
Soluble oligomers of amyloid-β peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway
Catherine Malaplate-Armand et al.
NEUROBIOLOGY OF DISEASE (2006)
Amyloid beta peptide increases DP5 expression via activation of neutral sphingomyelinase and JNK in oligodendrocytes
SW Chen et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Tetracyclines: Nonantibiotic properties and their clinical implications
AN Sapadin et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2006)
Inhibitory effect of minocycline on amyloid β fibril formation and human microglial activation
A Familian et al.
GLIA (2006)
Minocycline up-regulates BCL-2 levels in mitochondria and attenuates male germ cell apoptosis
M Castanares et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Antioxidant properties of minocycline: neuroprotection in an oxidative stress assay and direct radical-scavenging activity
RL Kraus et al.
JOURNAL OF NEUROCHEMISTRY (2005)
UV-C light induces raft-associated acid sphingomyelinase and JNK activation and translocation independently on a nuclear signal
A Charruyer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Protective effects of S-nitrosoglutathione against amyloid β-peptide neurotoxicity
TC Ju et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
A mitochondrial pool of sphingomyelin is involved in TNFα-induced Bax translocation to mitochondria
H Birbes et al.
BIOCHEMICAL JOURNAL (2005)
Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury
DP Stirling et al.
JOURNAL OF NEUROSCIENCE (2004)
Inhibitory action of minocycline on lipopolysaccharide-induced release of nitric oxide and prostaglandin E2 in BV2 microglial cells
SS Kim et al.
ARCHIVES OF PHARMACAL RESEARCH (2004)
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease
RG Cutler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development of Alzheimer's disease
AV Alessenko et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2004)
Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway
JT Lee et al.
JOURNAL OF CELL BIOLOGY (2004)
Inflammatory mediator and β-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E
K Ayasolla et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
The pathophysiology of mitochondrial cell death
DR Green et al.
SCIENCE (2004)
Fibrillar amyloid-β peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase -: Implications for Alzheimer's disease
A Jana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Clustering of death receptors in lipid rafts initiates neutrophil spontaneous apoptosis
D Scheel-Toellner et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2004)
Glucosylceramide synthase activity and ceramide levels are modulated during cerebral ischemia after ischemic preconditioning
K Takahashi et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2004)
Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats
Lin Xu et al.
BMC NEUROLOGY (2004)
Upregulation of ceramide and its regulating mechanism in a rat model of chronic cerebral ischemia
R Ohtani et al.
BRAIN RESEARCH (2004)
Neutral sphingomyelinase activation in endothelial and glial cell death induced by amyloid beta-peptide
DI Yang et al.
NEUROBIOLOGY OF DISEASE (2004)
Inhibition of sphingomyelinase activity helps to prevent neuron death caused by ischemic stress
S Soeda et al.
NEUROCHEMISTRY INTERNATIONAL (2004)
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
JZ Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease
X Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Mitochondrial intermembrane proteins in cell death
M van Gurp et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Membrane dynamics and cell polarity: the role of sphingolipids
D Hoekstra et al.
JOURNAL OF LIPID RESEARCH (2003)
Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis
RG Cutler et al.
ANNALS OF NEUROLOGY (2002)
Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis
XL Han et al.
JOURNAL OF NEUROCHEMISTRY (2002)
The ceramide-centric universe of lipid-mediated cell regulation: Stress encounters of the lipid kind.
YA Hannun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury
KL Arvin et al.
ANNALS OF NEUROLOGY (2002)
Minocycline delays disease onset and mortality in a transgenic model of ALS
L Van Den Bosch et al.
NEUROREPORT (2002)
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
S Zhu et al.
NATURE (2002)
Activation of mitochondrial, ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of bax translocation and cytochrome c release
D Liu et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2002)
Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease
YS Du et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis
H Birbes et al.
FASEB JOURNAL (2001)
Cell permeable exogenous ceramide reduces infarct size in spontaneously hypertensive rats supporting in vitro studies that have implicated ceramide in induction of tolerance to ischemia
K Furuya et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2001)
Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria
D Ardail et al.
FEBS LETTERS (2001)
Lethal forebrain ischemia stimulates sphingomyelin hydrolysis and ceramide generation in the gerbil hippocampus
M Nakane et al.
NEUROSCIENCE LETTERS (2000)
Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis
ZF Yu et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2000)
Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice
DX Chen et al.
NATURE MEDICINE (2000)
Ceramide initiates NFκB-mediated caspase activation in neuronal apoptosis
JS Gill et al.
NEUROBIOLOGY OF DISEASE (2000)