期刊
FREE RADICAL BIOLOGY AND MEDICINE
卷 77, 期 -, 页码 82-94出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.freeradbiomed.2014.09.007
关键词
Hydrogen sulfide; Persulfides; Polysulfides; Thiols; Thiol redox
资金
- Marie Curie International Reintegration Grant [PIRG08-GA-2010-277006]
Hydrogen sulfide (H2S) is an endogenously generated and putative signaling/effector molecule. Despite its numerous reported functions, the chemistry by which it elicits its functions is not understood. Moreover, recent studies allude to the existence of other sulfur species besides H2S that may play critical physiological roles. Herein, the basic chemical biology of H2S as well as other related or derived species is discussed and reviewed. This review particularly focuses on the per- and polysulfides which are likely in equilibrium with free H2S and which may be important biological effectors themselves. (C) 2014 Elsevier Inc. All rights reserved.
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