期刊
FREE RADICAL BIOLOGY AND MEDICINE
卷 49, 期 2, 页码 122-129出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.freeradbiomed.2010.03.009
关键词
Nitric oxide; EPR; Electron paramagnetic resonance spectroscopy; Hemoglobin; Free radicals
资金
- National Institutes of Health [GM55792, HL090503]
- National Biomedical EPR Center in the Biophysics Department at the Medical College of Wisconsin [P41-EB001980]
Electron paramagnetic resonance (EPR) spectroscopy has been used in a number of ways to study nitric oxide chemistry and biology. As an intrinsically stable and relatively unreactive diatomic free radical, the challenges of detecting this species by EPR are somewhat different from those of transient radical species. This review gives a basic introduction to EPR spectroscopy and discusses its uses to assess and quantify nitric oxide formation in biological systems. (C) 2010 Elsevier Inc. All rights reserved.
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