4.4 Article

Antioxidant and Anti-inflammatory Activities of Different Solvent Fractions from Ethanol Extract of Synurus deltoides (Aiton) Nakai Leaves

期刊

FOOD SCIENCE AND BIOTECHNOLOGY
卷 22, 期 1, 页码 215-223

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KOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST
DOI: 10.1007/s10068-013-0030-z

关键词

anti-inflammatory; antioxidant; cytotoxicity; DNA damage protection; phenolic content

资金

  1. Rural Development Administration, Korea [C1008514-01-01]

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Fractions of Synurus deltoides (Aiton) Nakai leaves showed excellent antioxidant and anti-inflammatory effects in a series of antioxidant and anti-inflammatory assays including total phenolic and flavonoid contents determination assay, DPPH free radical scavenging assay, reducing power assay, superoxide radical scavenging assay, nitrite scavenging assay, total antioxidant assay, DNA damage protection assay, MTT assay, nitric oxide (NO) production inhibition assay, and reverse transcription (RT)-PCR assay. The ethyl acetate fraction exhibited stronger antioxidant effects than other fractions in most of antioxidant assays such as DPPH assay, reducing power assay, superoxide radical scavenging assay, and nitrite scavenging assay. However, the dichloromethane fraction showed the strongest total antioxidant activity and NO production inhibitory activity. It was demonstrated that S. deltoides was valuable to be researched farther and application and fractions of S. deltoides had great potential to be a source of edible antioxidant and anti-inflammatory agents.

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