期刊
FOOD SCIENCE AND BIOTECHNOLOGY
卷 20, 期 5, 页码 1283-1288出版社
KOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST
DOI: 10.1007/s10068-011-0177-4
关键词
aromadendrin; diabetes; diabetes complication; Opuntia ficus-indica; prickly pear
资金
- Ministry of Knowledge Economy through the Center for Efficacy Assessment and Development of Functional Foods and Drugs at Hallym University
- National Research Foundation of Korea [NRF-2011-0009695]
- Hallym University
Prickly pear (Opuntia ficus-indica) is a long-domesticated crop plant of arid and semiarid parts of the world. The efficacy of extracts of prickly pear root for managing diabetes and diabetes complications was evaluated using a variety of in vitro bioassays. The ethyl acetate-soluble fraction was most effective in the prevention of diabetes and its complications via the inhibition of rat lens aldose reductase activity, the formation of advanced glycation end products, and alpha-glucosidase activity. MS and NMR were used to identify the bioactive compound from the ethyl acetate-soluble fraction as 3,5,7,4'-tetrahydroxyflavanone (aromadendrin).
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