期刊
FOOD CONTROL
卷 26, 期 1, 页码 63-67出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodcont.2012.01.004
关键词
Mycotoxin; Ochratoxin A; India; Wheat grains; HPLC
资金
- Council of Scientific and Industrial Research (CSIR)
- University Grants Commission (UGC), New Delhi
- CSIR Network [NWP 17]
Ochratoxin A (OTA), a mycotoxin produced by different species of Aspergillus and Penicillium spp of fungi, occurs in cereal grains, spices, coffee beans and various types of cereal products. OTA toxicity in animals is well documented and is suspected to be a carcinogen for human. In the present study, fifty wheat samples were collected from northern states of India for investigation of OTA levels using HPLC attached with a fluorescence detector utilizing acetonitrile-water-acetic acid (99:99:2, v/v/v) mixture as mobile phase. The Limit of Quantitation (LOQ) was 0.71 mu g kg(-1), and the average recovery values of OTA ranged from 71 to 92%. It was observed that 29 (58%) wheat samples were contaminated with detectable quantity of OTA ranging from 1.36 to 21.17 mu g kg(-1) including 13 (26%) samples exceeding the level of 5 mu g kg(-1) suggested by European Union. Based on the consumption of wheat in different states of India, the intake of OTA was found to saturate the provisional tolerable weekly intake (PTWI) to an extent of 0.97-2.49 folds for mean values in adult population. Overall, the study provides evidence for possible contamination of wheat produce thereby leading to exposure risk in Indian population. (C) 2012 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据