期刊
FOOD CHEMISTRY
卷 136, 期 1, 页码 94-99出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2012.07.101
关键词
Passiflora edulis Sims; C-deoxyhexosyl flavone; Flavonoid; Neurite outgrowth enhancing activity
资金
- Chinese Academy of Sciences [0931211022]
- Yunnan provincial government [20080A007, 2010BC003]
The stems and leaves of Passiflora edulis Sims, are used as a folk medicine for treating both anxiety and nervousness in American countries. Phytochemical investigation of the n-butanol (n-BuOH) fraction of this plant led to the isolation of four new 2,6-dideoxyhexose-C-glycosyl flavones, including luteolin-8-C-beta-digitoxopyranosyl-4'-O-B-D-glucopyranoside (1), apigenin-8-C-beta-digitoxopyranoside (2), apigenin-8-C-beta-boivinopyranoside (3) and luteolin-8-C-beta-boivinopyranoside (4), together with five known compounds (5-9). The structures of these compounds were elucidated by extensive spectroscopic methods. All compounds were evaluated for their neurite outgrowth enhancing activities and the results indicated that luteolin (7) enhanced NGF-induced neurite outgrowth in PC12 cells at 50.0 mu M. Crown Copyright (C) 2012 Published by Elsevier Ltd. All rights reserved.
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