期刊
FOOD CHEMISTRY
卷 120, 期 1, 页码 339-342出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2009.09.073
关键词
Apple pomace; Antioxidant; Antiviral; Herpes
资金
- Regional Government of the Principality of Asturias
- Town Hall of Villaviciosa
Methanolic and acetonic extracts of apple pomace were evaluated for phenolic profiles, antioxidant properties and antiviral effect against herpes simplex virus type 1 (HSV-1) and 2 (HSV-2). Acetone extraction yielded the higher amounts of phenolic compounds. The extraction method influenced the phenolic composition although antioxidant activity correlated weakly with phenols concentration. Among the polyphenols analysed, quercetin glycosides were the most important family, followed by dihydrochalcones. Apple pomace extracts were able to inhibit both HSV-1 and HSV-2 replication in Vero cells by more than 50%, at non-cytotoxic concentrations. Selectivity indexes (SI) ranged from 9.5 to 12.2. (C) 2009 Elsevier Ltd. All rights reserved.
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