期刊
FOOD CHEMISTRY
卷 115, 期 2, 页码 697-700出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2008.12.063
关键词
Delivery system; Lysozyme; Supercritical anti-solvent; Zein
资金
- University of Tennessee Agricultural Experiment Station
Delivery systems with sustained release of antimicrobials are possible solutions to minimize the binding between antimicrobials and food matrices, thereby enhancing the efficacy of antimicrobials during shelf-lives of foods. In this work, GRAS (generally recognized as safe) corn zein was used as a carrier material and 90% aqueous ethanol was used as a solvent to microencapsulate GRAS hen egg white lysozyme using a supercritical anti-solvent (SAS) process. The microcapsules showed a continuous matrix with internal voids. The release of lysozyme was observed over 36 days at room temperature, with slower release at a higher pH between 2 and 8. At pH 4, release kinetics was further slowed by the addition of sodium chloride. Stronger molecular attraction between lysozyme and carrier zein was attributed to slower release at a higher pH and a higher ionic strength at the same pH. Our work demonstrated that SAS may be a feasible process to manufacture GRAS delivery systems to enhance antimicrobial efficacy. (C) 2008 Elsevier Ltd. All rights reserved.
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