期刊
FOOD AND CHEMICAL TOXICOLOGY
卷 50, 期 3-4, 页码 1109-1117出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fct.2012.01.004
关键词
UVB photoprotection; Zebrafish embryos; Seaweed polyphenols; Ochrophyta; Rhodophyta; Total phenolic content (TPC)
资金
- Comunidad Autonoma de Madrid
- EU
- IFC (Industrial Farmaceutica Cantabria, Spain)
- ZF Biolabs
The photoprotective potential against UVB radiation of extracts obtained from 21 commercial macroalgae from the Phyla Ochrophyta and Rhodophyta, was evaluated in vivo, using the zebrafish embryo as a whole model organism. Our results showed that the phenolic extracts from Macrocystis pyrifera and Porphyra columbina exhibited the highest photoprotective activity, close to complete photoprotection (100%), similar to that obtained for the carrageenophytes Sarcothalia radula and Gigartina skottsbergii. Under the assayed conditions, the extracts were safe and non-toxic to the embryos at a concentration of 0.04 mg/ml PGE. (C) 2012 Elsevier Ltd. All rights reserved.
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