期刊
FOOD AND CHEMICAL TOXICOLOGY
卷 49, 期 12, 页码 3358-3366出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fct.2011.09.013
关键词
Copper supplementation; Intensive systems; Cattle; Toxic and essential metals; Correlations; Metal disorders
资金
- Xunta de Galicia (Spain) [07MRU030261PR]
- Direccion Xeral de Investigacion, Desenvolvemento e Innovacion from Xunta de Galicia
- FSE (Fondo Social Europeo)
The aim of this study is to evaluate if dietary Cu supplementation that leads to a hepatic Cu accumulation over the normal range has an influence on trace element status that could contribute to the pathogenesis of other mineral related disorders. Samples (liver, kidney, spleen, diaphragm and brain) of beef calves receiving typical commercial diets Cu supplemented and non-supplemented were tested for differences in non-essential and essential trace elements determined by ICP-MS. As (kidney and diaphragm). Hg (liver and kidney), and Pb (liver, kidney and spleen) were significantly lower, while Cd residues (liver and kidney) were significantly higher in the Cu supplemented group. Mn and Ni significantly decreased and Mo increased in the brain, and Se (diaphragm) decreased in the Cu supplemented group. These interactions are unknown, and possibly with more than two metals involved as suggested in the case of the ratio Se:Cu in the animals of this study. The possible role of Cu supplementation on the status of certain metals associated to neurological diseases (Mn-Ni) in the brain deserves further investigation. Finally new research on Cu-Se supplementation is necessary to better understand the risk of the animals to suffer from Se deficiency. (C) 2011 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据