Application of Polymer Monolith Microextraction to the Determination of Triazines in Cereal Samples Combined with High-Performance Liquid Chromatography

A simple and sensitive method based on polymer monolith microextraction (PMME) using a poly(methacrylic acid-co-ethylene glycol dimethacrylate) (poly(MAA-EGDMA)) monolith has been developed for the determination of triazines combined with high-performance liquid chromatography. The method is evaluated with several parameters including linear range, limits of detection, limits of quantification, and reproducibility after optimizing PMME experimental conditions. Sample flow rate, sample volume, eluent flow rate, and sample pH have been investigated and optimized in detail with respect to extraction efficiency of the target compounds from cereal samples. Good linearities are obtained for six triazines with the correlation coefficients (R (2)) above 0.9977. Limits of detection based on three times of standard deviations of blank by seven replicates are in the range of 1.1-2.8 mu g kg(-1). Good reproducibility of the method is obtained, yielding the intra-day and inter-day relative standard deviations less than 4.3% and 5.5%, respectively. The method has been proved to be efficient, fast, and sensitive for the quantitative analysis of triazines in practical cereal samples.