期刊
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA
卷 46, 期 1, 页码 23-38出版社
VIA MEDICA
DOI: 10.2478/v10042-008-0003-x
关键词
cathepsin D; procathepsin D; preprocathepsin D; aspartic proteinase
A literature survey was performed of human cathepsin D gene, cathepsin D biosynthesis, posttranslatory modifications, transport within the cell, substrate specificity and catalytic effect. Methods used to determine the activity and level of this proteinase as well as its role in the biochemistry and pathobiochemistry of cells, tissues and organs were considered.
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