期刊
FITOTERAPIA
卷 95, 期 -, 页码 214-219出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2014.03.026
关键词
Desmodium renifolium; Prenylated chalcone; Cytotoxicity
资金
- National Natural Science Foundation of China [21302164]
- Excellent Scientific and Technological Team of Yunnan High School [2010CI08]
- Yunnan University of Nationalities Green Chemistry and Functional Materials Research for Provincial Innovation Team [2011HC008]
- Open Research Fund Program of the Key Laboratory of Ethnic Medicine Resource Chemistry (Yunnan University of Nationalities) [2010XY08]
Five unusual new prenylated chalcones, renifolins D-H (1-5), were isolated from whole Desmodium renifolium plants. All of their structures were determined by spectroscopic methods including 1D and 2D NMR. All of the isolates were evaluated for cytotoxicity using five tumor cell lines. Compounds 2 and 3 exhibited cytotoxicity against A549 cells, with IC50 values of 2.8 and 22 mu M, respectively. (C) 2014 Elsevier B.V. All rights reserved.
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