期刊
FITOTERAPIA
卷 83, 期 1, 页码 44-48出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2011.09.010
关键词
Epimedium wushanense; Berberidaceae; Flavonoid; DPPH; Antioxidant
资金
- Peking University Health Science Center [985-2-119-121]
Two new flavonoids, wushanicaritin (1) and wushankaempferol (2), along with 24 known flavonoids were isolated from the whole herb of Epimedium wushanense T.S. Ying (Berberidaceae). On the basis of NMR and ESI-MS spectroscopic analysis, structures of compounds 1 and 2 were elucidated as 8-gamma-hydroxy-y-gamma,gamma-dimethylpropyl-3,5,7-trihydroxy-4'. methoxyflavone and kaempferol 3-O-alpha-L-[2,3-di-O-beta-D-(6-E-p-coumaroyl) glucopyranosyl]-rhamnopyranosyl-7-O-alpha-L-rhamnopyranoside, respectively. DPPH radical scavenging activity tests indicated that 1 (IC50 35.3 mu M) exhibited antioxidant activity comparable to Vitamin C (IC50 32.0 mu M). while 2 (IC50 443.7 mu M) showed weak activity. (C) 2011 Elsevier B.V. All rights reserved.
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