Cytotoxicity of chemical constituents from the stems of Dalbergia parviflora

Three new compounds, dalberpene (1), dalparvinene B (2) and dalparvone B (3), as well as 12 known compounds were isolated from the heartwood of Dalbergia parviflora. Isoflavanone 13 showed strong cytotoxicity against KB. MCF-7 and NCI-H187 cell lines with IC50 values ranging from 3.5 to 5.4 mu g/mL and it was inactive against normal cells. (C) 2011 Elsevier B.V. All rights reserved.