期刊
FITOTERAPIA
卷 80, 期 5, 页码 301-305出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2009.03.009
关键词
Pomegranate; Polyphenols; Thrombin inhibition
Pomegranate (Punica granatum) is an important source of polyphenols with assessed antioxidant properties. The aims of this study were: (i) the characterization of the monomeric phenolic variability on each isolated fruit component (endocarp, mesocarp, aril); (ii) the study on the effect of pomegranate fruit components on human thrombin amidolytic activity. Collectively, our data show that pomegranate components contain bioactive metabolites (mainly ellagic acid) and suggest a potential role for the pomegranate extract in the regulation of a number of physiopathological processes involving thrombin (or thrombin-like proteinase). (C) 2009 Published by Elsevier B.V.
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