期刊
FITOTERAPIA
卷 80, 期 6, 页码 339-344出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2009.04.007
关键词
Phenolic acids; Saponin; Glycation; Nutraceutical; Ilex paraguariensis
资金
- FAPESP (Brazil)
- Touro University
The present study concentrates on the evaluation of the anti-glycation effect of some bioactive substances present in yerba mate (Ilex paraguariensis): 5-caffeoylquinic acid, caffeic acid and a sapogenin (oleanolic acid). Bovine serum albumin and histones were incubated in the presence of methylglyoxal with or without the addition of 5-caffeoylquinic acid, caffeic acid and oleanolic acid. After the incubation period, advanced glycation end product (AGE) fluorescence spectra were performed and protein structural changes were evaluated by Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis. Chlorogenic acid, caffeic acid are the main substances responsible for the anti-glycation effect of mate tea. (C) 2009 Elsevier B.V. All rights reserved.
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