期刊
FISH PHYSIOLOGY AND BIOCHEMISTRY
卷 36, 期 1, 页码 101-107出版社
SPRINGER
DOI: 10.1007/s10695-008-9295-1
关键词
Metallothionein; Trace metals; Organs; Sparus aurata
资金
- Ministry of Scientific Research and Technology, Tunisia
The levels of metallothionein (MT), a biomarker of metal exposure, and of Cd and Cu, known as MT inducers, were investigated in Sparus aurata intraperitoneally injected with 500 mu g/kg of Cu and Cd for 2 days. MT and metal concentrations (Cd and Cu) were determined in liver, gills and kidney. MT levels were significantly increased in all investigated tissues, with the highest value in liver of Cu as Cd-treated fishes (3.56-fold and 3.3- fold, respectively). Metal concentrations were statistically different between all tissues. Highest metal concentrations were in the liver. The higher metal concentrations and MT induction levels support the main role of MT in metal homeostasis and detoxification.
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