期刊
FISH & SHELLFISH IMMUNOLOGY
卷 38, 期 1, 页码 149-157出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fsi.2014.03.002
关键词
Astragalus polysaccharides; Tilapia nilotica; Growth performance; Immunomodulation; Intestinal histology
资金
- Department of Fish Diseases, Faculty of Veterinary Medicine, Mansoura University
- Department of Pathology, Faculty of Veterinary Medicine, Mansoura University
- Department of Clinical Pathology, Faculty of Veterinary Medicine, Mansoura University
This work investigated the potential immunomodulatory and growth-promoting effects of Astragalus polysaccharides CAPS) in Nile tilapia (Oreochromis niloticus). The dietary supplementation with APS (1500 mg/kg of diet) caused a significant increase in growth parameters (initial and final weight, weight gain (WG), specific growth rate (SGR), feed conversion ratio (FCR) and feed intake (FI), when compared to non-supplemented control basal diet. In addition, APS upregulated the phagocytic activity, the respiratory burst activity, plasma lysozyme, the bactericidal activity, superoxide dismutase (SOD), glutathione peroxidase (GPx), and amylase activity. However, it had no effect on serum nitric oxide (NO) or Malondialdehyde (MDA) levels. While APS had no effect of intestinal histology, a slight increase in the villi length was recorded. Collectively, our results indicate that dietary APS supplementation could improve the growth performance and the immune parameters of cultured tilapia fish. (C) 2014 Elsevier Ltd. All rights reserved.
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