Process technology and properties evaluation of a chitosan-coated Tencel/cotton nonwoven fabric as a wound dressing

A double-layer nonwoven fabric containing Tencel, cotton, and chitosan was prepared by the immersion-precipitation phase-inversion method and evaluated as a wound covering. Macroporous structure of the chitosan membrane could control evaporative water loss, promote fluid drainage, and inhibit exogenous micro-organisms invasion due to inherent antimicrobial property of the chitosan. The chitosan membrane was hemaostatic and could accelerate the healing of the wound. Histological examination showed that epithelialization rate was increased and the deposition of collagen in the dermis was well organized by covering the wound with the membrane. These results indicate that the chitosan-coated Tencel/cotton nonwoven fabric can be a potential material employed as a wound dressing.