期刊
FETAL AND PEDIATRIC PATHOLOGY
卷 31, 期 5, 页码 265-272出版社
INFORMA HEALTHCARE
DOI: 10.3109/15513815.2012.659381
关键词
phimosis; topical corticosteroid; collagen fibers; inflammatory infiltrate
资金
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
- Fundacao de Amparo a Pesquisa do Estado de Minas Gerais (FAPEMIG)
- Fundacao de Ensino e Pesquisa de Uberaba (FUNEPU)
Problems with the foreskin are common reasons for pediatric surgery consultations. We collected the foreskin of 40 patients for 2 years and these samples were divided into groups with and without previous topical corticosteroid. We carried out histochemical hematoxylin & eosin and Picrosirius analyses of the foreskin. Collagen fibers and inflammatory infiltrate was higher in samples from patients who had complications related to phimosis. Fibrosis was higher in patients who used topical corticosteroid. A histopathologic study of the foreskin may provide an additional analysis of patients undergoing circumcision and it can also improve the accuracy of surgical indication.
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