期刊
FERTILITY AND STERILITY
卷 95, 期 8, 页码 2745-2748出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2011.03.112
关键词
Sperm; semenogelin II precursor; prolactin-induced protein; clusterin; prostate-specific antigen
资金
- NCRR NIH HHS [S10 RR031537, UL1 RR024989] Funding Source: Medline
In this study, the sperm protein profile was compared between fertile and infertile men using 2-dimensional gel electrophoresis, liquid chromatography mass spectrometer analysis, and matrix-assisted laser desorption ionization-time-of-flight-mass spectrometry. Four unique proteins, semenogelin II precursor, prolactin-induced protein, clusterin isoform 1, and prostate-specific antigen isoform 1 preproprotein, were predominantly present in the semen of healthy men; however, semenogelin II precursor and clusterin isoform 1 were not seen in the semen of infertile men, suggesting unique differences in the spermatozoa protein profiles of fertile and infertile men. (Fertil Steril (R) 2011;95:2745-8. (C)2011 by American Society for Reproductive Medicine.)
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