The effect of aromatase inhibitor letrozole on body mass index, serum hormones, and sperm parameters in infertile men

We investigated the effect of letrozole, an aromatase inhibitor, on body mass index, serum hormones, and sperm parameters in infertile men with decreased T:E-2 ratios. All sperm parameters increased after letrozole treatment. Letrozole may be effectively used to improve sperm parameters in infertile men with a low serum T:E-2 ratio. (Fertil Steril (R) 2011;95:809-11. (C)2011 by American Society for Reproductive Medicine.)