期刊
FERTILITY AND STERILITY
卷 95, 期 4, 页码 1497-U350出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2010.12.023
关键词
IVM; preantral follicles; CRH; CRH-R1; antalarmin
The expression of corticotropin-releasing hormone (CRH) receptor 1 messenger RNA in stages of follicle growth was examined by reverse transcriptase-polymerase chain reaction in long-term cultures of early preantral mouse follicles with and without CRH addition. Corticotropin-releasing hormone receptor 1 is present in stages of mouse follicle growth, whereas 10(-9), 10(-7), and 10(-6) mol/L CRH inhibits oocyte maturation in vitro, an effect reversed by antalarmin addition. (Fertil Steril (R) 2011;95:1497-9. (C) 2011 by American Society for Reproductive Medicine.)
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