期刊
FERTILITY AND STERILITY
卷 94, 期 2, 页码 781-U426出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2009.10.020
关键词
Epigenetics; DNA methylation; polycystic ovary syndrome
资金
- NCRR NIH HHS [M01 RR000425-41, M01-RR00425, M01 RR000425] Funding Source: Medline
- NICHD NIH HHS [R01-HD29364, R01 HD029364-12, K24-HD01346, R01 HD029364, K24 HD001346-06, K24 HD001346] Funding Source: Medline
- NIDDK NIH HHS [R01-DK79888, R01 DK079888, R01 DK079888-02] Funding Source: Medline
The percent global methylation of peripheral blood DNA was not significantly altered in 20 women with polycystic ovary syndrome (PCOS) compared with 20 controls. The study of specific tissues and target genomic regions will be required to further determine whether epigenetic alteration influences the development of PCOS. (Fertil Steril (R) 2010;94:781-3. (C) 2010 by American Society for Reproductive Medicine.)
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