A healthy birth after intracytoplasmic sperm injection using ejaculated spermatozoa from a patient with Kartagener's syndrome

Objective: To report a healthy birth that was achieved by intracytoplasmic sperm injection (ICSI) with use of ejaculated spermatozoa from a patient with Kartagener's syndrome. Design: Case report. Setting: Private infertility clinic. Patient(s): Couple with male factor infertility due to Kartagener's syndrome. Intervention(s): Intracytoplasmic sperm injection with ejaculated sperm. Main Outcome Measure(s): Semen characteristics, sperm motility, fertilization, pregnancy, and birth after ICSI. Result(s): With ejaculated sperm, the fertilization rates were 73% in the first stimulation cycle and 100% in the second cycle. Intracytoplasmic sperm injection was successful. The pregnancy resulted in birth of a single healthy child. Conclusion(s): With ejaculated sperm, successful pregnancy after ICSI in couples with Kartagener's syndrome is possible. Kartagener's syndrome is a heterogeneous group of disorders with similar clinical presentations, and treatment should be individualized depending on sperm motility. (Fertil Steril (R) 2010;93:2074.e17-e19. (C) 2010 by American Society for Reproductive Medicine.)