Reduced serum ghrelin in a putative postmenopausal polycystic ovary syndrome phenotype

We measured fasting serum ghrelin concentrations in a cohort of community-dwelling postmenopausal women with a putative polycystic ovary syndrome (PCOS) phenotype. Ghrelin levels were reduced in women with the phenotype compared with nonaffected control women, supporting our hypothesis that a phenotype analogous to PCOS can be identified in postmenopausal women. (Fertil Steril (R) 2009;92:1753-4. (C) 2009 by American Society for Reproductive Medicine.)