4.7 Article

Acyl-CoA synthetase long-chain family member 6 is associated with premature ovarian failure

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FERTILITY AND STERILITY
卷 91, 期 4, 页码 1339-1343

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ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2008.03.035

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  1. Ministry of Health & Welfare, Republic of Korea [01-PJ10-PG6-01GN13-0002, 0405-BC02-0604-0004]

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To identify genes that are associated with premature ovarian failure, a linkage disequilibrium-based genome-wide association study with dense single nucleotide polymorphisms as genetic markers was performed. The acyl-coenzyme A synthetase long-chain family member 6 (ACSL6) gene on chromosome 5q31 was associated with premature ovarian failure and identified disease-susceptibility haplotypes. (Fertil Steril (R) 2009;91: 1339-43. (C)2009 by American Society for Reproductive Medicine.)

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