期刊
FERTILITY AND STERILITY
卷 91, 期 4, 页码 1451-1454出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2008.07.012
关键词
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资金
- National Institute of Child Health and Human Development
- National Institutes of Health [U54-HD041857]
This study investigated the regulation of Wilms' tumor gene (WT1) in the ovary by nerve growth factor and FSH to better understand signals that initiate early follicular growth. Nerve growth factor showed a direct stimulatory effect on endogenous expression of WT1, whereas FSH attenuated basal and nerve growth factor-stimulated WT1 protein expression, which most likely depended on FSH responsiveness according to the follicle growth stage. (Fertil Steril (R) 2009;91:1451-4. (C) 2009 by American Society for Reproductive Medicine.)
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