期刊
FEMS YEAST RESEARCH
卷 12, 期 1, 页码 97-101出版社
OXFORD UNIV PRESS
DOI: 10.1111/j.1567-1364.2011.00759.x
关键词
Saccharomyces cerevisiae; cell volume; replicative aging; budding; cell cycle; hypertrophy
资金
- Polish Ministry of Science and Higher Education [N N303 376436]
This paper summarizes numerous arguments demonstrating that the hypothesis of accumulation of the senescence factor, which was the basis for introducing yeast to the group of model organisms of gerontology, finds no experimental support. Among several candidates for the role of the causative agents of replicative aging, only one hypertrophy always accompanies symptoms of aging, not only in Saccharomyces cerevisiae, but also in Schizosaccharomyces pombe.
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