期刊
FEMS MICROBIOLOGY LETTERS
卷 343, 期 2, 页码 169-176出版社
OXFORD UNIV PRESS
DOI: 10.1111/1574-6968.12143
关键词
lipopolysaccharide; avian; egg; oviduct; ovary
类别
资金
- BBSRC [BB/F007221/1, BB/F007973/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [B1502/28, BB/F007221/1, BB/F007973/1] Funding Source: Medline
- Biotechnology and Biological Sciences Research Council [BB/F007221/1, BB/F007973/1] Funding Source: researchfish
Salmonella enterica serovar Enteritidis is a major cause of human gastrointestinal disease, infection being due in large part to consumption of contaminated eggs. The lipopolysaccharide (LPS) of Salmonella is known to play a role in colonisation of the host and survival in hostile conditions including egg albumen. We investigated the contribution of LPS O-antigen length to colonisation of the reproductive tract of laying hens, contamination of eggs and survival in albumen. We show that expression of very-long O-antigen is essential for contamination of eggs, probably as a consequence of enhanced reproductive tract colonisation and survival in the forming egg.
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