A facile and efficient one-pot synthesis of 6-amino-2-oxo-4-aryl-4H-1,3-dithiine-5-carbonitrile derivatives in water

A one-pot three-component synthesis of 6-amino-2-oxo-4-aryl-4H-1,3-dithiine-5-carbonitriles from amines, carbon disulfide, and arylidenemalononitriles in H2O under reflux conditions, in good yields, is described.