期刊
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
卷 53, 期 1, 页码 1-7出版社
WILEY
DOI: 10.1111/j.1574-695X.2008.00378.x
关键词
toll-like receptors; fungal pathogens; paracoccidioidomycosis; TLR2; TLR4; MyD88
The aim of this minireview is to present a concise view of the most important pattern recognition receptors used by the innate immune system to sense and control pathogen growth into host tissues. A brief review of the role of Toll-like receptors (TLRs) in fungal infections followed by some recent results on the function of TLR4, TLR2 and the MyD88 adaptor molecule in the pathogenesis of paracoccidioidomycosis are presented.
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