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A dominant negative Cx43 mutant differentially affects tumorigenic and invasive properties in human metastatic melanoma cells
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BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)
MAPK Phosphorylation of Connexin 43 Promotes Binding of Cyclin E and Smooth Muscle Cell Proliferation
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The gap junction protein Cx43 is involved in the bone-targeted metastatic behaviour of human prostate cancer cells
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Connexin 43 interacts with Bax to regulate apoptosis of pancreatic cancer through a gap junction-independent pathway
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Cx31.1 acts as a tumour suppressor in non-small cell lung cancer (NSCLC) cell lines through inhibition of cell proliferation and metastasis
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The Tumor-Suppressive Function of Connexin43 in Keratinocytes Is Mediated in Part via Interaction with Caveolin-1
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Amino Acid Residue Val362 Plays a Critical Role in Maintaining the Structure of C Terminus of Connexin 50 and in Lens Epithelial-fiber Differentiation
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JOURNAL OF CELLULAR BIOCHEMISTRY (2010)
Enhanced Connexin 43 Expression Delays Intra-Mitoitc Duration and Cell Cycle Traverse Independently of Gap Junction Channel Function
Scott R. Johnstone et al.
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Connexin 43 regulates astrocytic migration and proliferation in response to injury
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Connexin43 inhibits the oncogenic activity of c-Src in C6 glioma cells
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Oxidized Phospholipid Species Promote in Vivo Differential Cx43 Phosphorylation and Vascular Smooth Muscle Cell Proliferation
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AMERICAN JOURNAL OF PATHOLOGY (2009)
Gap Junctions and Cancer: New Functions for an Old Story
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Exogenous Cx43 expression decrease cell proliferation rate in rat hepatocarcinoma cells independently of functional gap junction
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Phosphorylation of connexin-43 at serine 262 promotes a cardiac injury-resistant state
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CARDIOVASCULAR RESEARCH (2009)
Connexins: a myriad of functions extending beyond assembly of gap junction channels
Hashem A. Dbouk et al.
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Connexin 32 increases the proliferative response of Schwann cells to neuregulin-1 (Nrg1)
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Connexin 43 recruits E-cadherin expression and inhibits the malignant behaviour of lung cancer cells
Hong-Tao Xu et al.
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA (2008)
Connexin 43 confers resistance to hydrogen peroxide-mediated apoptosis
Sarah F. Giardina et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Promotion of lens epithelial-fiber differentiation by the C-terminus of connexin 45.6 - a role independent of gap junction communication
Eric A. Banks et al.
JOURNAL OF CELL SCIENCE (2007)
Gap junction adhesion is necessary for radial migration in the neocortex
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NATURE (2007)
Enhancing effect of connexin 32 gene on vinorelbine-induced cytotoxicity in A549 lung adenocarcinoma cells
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CANCER CHEMOTHERAPY AND PHARMACOLOGY (2007)
Cytoplasmic accumulation of connexin32 protein enhances motility and metastatic ability of human hepatoma cells in vitro and in vivo
Qingchang Li et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Connexins in lens development and cataractogenesis
Xiaohua Gong et al.
JOURNAL OF MEMBRANE BIOLOGY (2007)
Cx43 mediates TGF-β signaling through competitive Smads binding to microtubules
Ping Dai et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
The modulatory effects of connexin 43 on cell death/survival beyond cell coupling
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PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2007)
Cx26 inhibits breast MDA-MB-435 cell tumorigenic properties by a gap junctional intercellular communication-independent mechanism
Jessica Kalra et al.
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Connexins act as tumor suppressors in three-dimensional mammary cell organoids by regulating differentiation and angiogenesis
Elizabeth McLachlan et al.
CANCER RESEARCH (2006)
Connexin 43-mediated modulation of polarized cell movement and the directional migration of cardiac neural crest cells
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Regulation of connexin-43-mediated growth inhibition by a phosphorylatable amino-acid is independent of gap junction-forming ability
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The gap junction cellular internet: connexin hemichannels enter the signalling limelight
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BIOCHEMICAL JOURNAL (2006)
Life cycle of connexins in health and disease
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Defective gap junctional intercellular communication in the carcinogenic process
M Mesnil et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2005)
Contribution of the Src family of kinases to the appearance of malignant phenotypes in renal cancer cells
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MOLECULAR CARCINOGENESIS (2005)
Gap junction- and hemichannel-independent actions of connexins
JX Jiang et al.
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Role of connexin 43 in ischemic preconditioning does not involve intercellular communication through gap junctions
X Li et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)
Transfer of biologically important molecules between cells through gap junction channels
DB Alexander et al.
CURRENT MEDICINAL CHEMISTRY (2003)
Gap junction communication mediates transforming growth factor-β activation and endothelial-induced mural cell differentiation
KK Hirschi et al.
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Stimulation of lens cell differentiation by gap junction protein connexin 45.6
SM Gu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Increased invasive capacity of connexin43-overexpressing malignant glioma cells
W Zhang et al.
JOURNAL OF NEUROSURGERY (2003)
Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Gap junctions and tumour progression
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Dual functions for connexins: Cx43 regulates growth independently of gap junction formation
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Connexin43 suppresses proliferation of osteosarcoma U2OS cells through post-transcriptional regulation of p27
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