期刊
FEBS LETTERS
卷 587, 期 19, 页码 3224-3230出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.febslet.2013.08.014
关键词
Egr-family; Immediate early gene; Honeybee
资金
- Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan
- Japan Society for the Promotion of Science for Young Scientists
- Grants-in-Aid for Scientific Research [23370032, 12J10515] Funding Source: KAKEN
To date, there are only few reports of immediate early genes (IEGs) available in insects. Aiming at identifying a conserved IEG in insects, we characterized an Egr homolog of the honeybee (AmEgr: Apis mellifera Egr). AmEgr was transiently induced in whole worker brains after seizure induction. In situ hybridization for AmEgr indicated that neural activity of a certain mushroom body (a higher brain center) neuron subtype, which is the same as that we previously identified using another non-coding IEG, termed kakusei, is more enhanced in forager brains. These findings suggest that Egr can be utilized as an IEG in insects. (C) 2013 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
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