相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Regulation Mechanisms and Signaling Pathways of Autophagy
Congcong He et al.
ANNUAL REVIEW OF GENETICS (2009)
Atg14 and UVRAG Mutually exclusive subunits of mammalian Beclin 1-PI3K complexes
Eisuke Itakura et al.
AUTOPHAGY (2009)
Evolution of Atg1 function and regulation
Edmond Y. Chan et al.
AUTOPHAGY (2009)
Rapamycin inhibits mTORC1, but not completely
Carson C. Thoreen et al.
AUTOPHAGY (2009)
3D tomography reveals connections between the phagophore and endoplasmic reticulum
Päivi Ylä-Anttila et al.
Autophagy (2009)
hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells
Ying Yan et al.
BIOCHEMICAL JOURNAL (2009)
Mitophagy
Aviva M. Tolkovsky
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Control of autophagy initiation by phosphoinositide 3-phosphatase jumpy
Isabelle Vergne et al.
EMBO JOURNAL (2009)
ULK1•ATG13•FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy
Ian G. Ganley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
Carson C. Thoreen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
Anne Simonsen et al.
JOURNAL OF CELL BIOLOGY (2009)
Nutrient-dependent mTORC1 Association with the ULK1-Atg13-FIP200 Complex Required for Autophagy
Nao Hosokawa et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation
Yu-Yun Chang et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
Chang Hwa Jung et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
The Vam6 GEF Controls TORC1 by Activating the EGO Complex
Matteo Binda et al.
MOLECULAR CELL (2009)
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation
Mitsuko Hayashi-Nishino et al.
NATURE CELL BIOLOGY (2009)
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
Yun Zhong et al.
NATURE CELL BIOLOGY (2009)
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
Kohichi Matsunaga et al.
NATURE CELL BIOLOGY (2009)
Mechanisms of amino acid sensing in mTOR signaling pathway
Eunjung Kim
NUTRITION RESEARCH AND PRACTICE (2009)
Dynamics and function of PtdIns(3)P in autophagy
Keisuke Obara et al.
AUTOPHAGY (2008)
BARgaining membranes for autophagosome formation: Regulation of autophagy and tumorigenesis by Bif-1/Endophilin B1
Yoshinori Takahashi et al.
AUTOPHAGY (2008)
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
Karine Lindmo et al.
AUTOPHAGY (2008)
Dissecting the localization and function of Atg18, Atg21 and Ygr223c
Roswitha Krick et al.
AUTOPHAGY (2008)
Bcl-2 family members - Dual regulators of apoptosis and autophagy
Beth Levine et al.
AUTOPHAGY (2008)
The regulation and function of Class III PI3Ks: novel roles for Vps34
Jonathan M. Backer
BIOCHEMICAL JOURNAL (2008)
Amino acids activate mTOR Complex 1 via Ca2+/CaM signaling to hVps34
Pawan Gulati et al.
CELL METABOLISM (2008)
Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae
Keisuke Obara et al.
GENES TO CELLS (2008)
The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila
Gabor Juhasz et al.
JOURNAL OF CELL BIOLOGY (2008)
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
Elizabeth L. Axe et al.
JOURNAL OF CELL BIOLOGY (2008)
Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease
Brinda Ravikumar et al.
JOURNAL OF CELL SCIENCE (2008)
Autophagosome supports coxsackievirus B3 replication in host cells
Jerry Wong et al.
JOURNAL OF VIROLOGY (2008)
Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG
Eisuke Itakura et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy
Yongjie Wei et al.
MOLECULAR CELL (2008)
Regulation of TORC1 by Rag GTPases in nutrient response
Eunjung Kim et al.
NATURE CELL BIOLOGY (2008)
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
Andrea Williams et al.
NATURE CHEMICAL BIOLOGY (2008)
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
Yasemin Sancak et al.
SCIENCE (2008)
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
Yoshinori Takahashi et al.
NATURE CELL BIOLOGY (2007)
A role for Rab5 in structuring the endoplasmic reticulum
Anion Audhya et al.
JOURNAL OF CELL BIOLOGY (2007)
The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco/endoplasmic reticulum calcium stores
Nathan R. Brady et al.
FEBS JOURNAL (2007)
BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-XL
Maria Chiara Maiuri et al.
AUTOPHAGY (2007)
The inositol trisphosphate receptor in the control of autophagy
Alfredo Criollo et al.
AUTOPHAGY (2007)
mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer
Stephen G. Dann et al.
TRENDS IN MOLECULAR MEDICINE (2007)
Role of class II phosphoinositide 3-kinase in cell signalling
M. Falasca et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Regulation of class III (Vps34) PI3Ks
Y. Yan et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-β, and Bcl-2
Maria Hoyer-Hansen et al.
MOLECULAR CELL (2007)
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
Chengyu Liang et al.
NATURE CELL BIOLOGY (2006)
Assortment of phosphatidylinositol 3-kinase complexes-Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae
K Obara et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes
EE Johnson et al.
JOURNAL OF CELL SCIENCE (2006)
Regulation of membrane traffic by phosphoinositide 3-kinases
K Lindmo et al.
JOURNAL OF CELL SCIENCE (2006)
TOR signaling in growth and metabolism
S Wullschleger et al.
CELL (2006)
Functional specificity of the mammalian Beclin-Vps34 Pl 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
XH Zeng et al.
JOURNAL OF CELL SCIENCE (2006)
TOR signaling in growth and metabolism
Stephan Wullschleger et al.
CELL (2006)
Autophagy: molecular machinery for self-eating
T Yorimitsu et al.
CELL DEATH AND DIFFERENTIATION (2005)
Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis
Y Takahashi et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 30H-kinase
T Nobukuni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase
MP Byfield et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
S Pattingre et al.
CELL (2005)
Autophagy in metazoans: Cell survival in the land of plenty
JJ Lum et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy
Y Kabeya et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
Norihiko Furuya et al.
AUTOPHAGY (2005)
A sorting nexin PpAtg24 regulates vacuolar membrane dynamics during pexophagy via binding to phosphatidylinositol-3-phosphate
Y Ano et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
The molecular machinery of autophagy: unanswered questions
DJ Klionsky
JOURNAL OF CELL SCIENCE (2005)
3-methyladenine inhibits autophagy in tobacco culture cells under sucrose starvation conditions
C Takatsuka et al.
PLANT AND CELL PHYSIOLOGY (2004)
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
A Simonsen et al.
JOURNAL OF CELL SCIENCE (2004)
Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy
PE Stromhaug et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
WIPI-1α (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy
T Proikas-Cezanne et al.
ONCOGENE (2004)
PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49
TR Jeffries et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
A unified nomenclature for yeast autophagy-related genes
DJ Klionsky et al.
DEVELOPMENTAL CELL (2003)
Calcium signalling: Dynamics, homeostasis and remodelling
MJ Berridge et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Human VPS34 and p150 are rab7 interacting partners
MP Stein et al.
TRAFFIC (2003)
Inhibition of autophagy in mitotic animal cells
EL Eskelinen et al.
TRAFFIC (2002)
Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase
P Burda et al.
JOURNAL OF CELL SCIENCE (2002)
Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy
DC Nice et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Retention of the yeast Sac1p phosphatase in the endoplasmic reticulum causes distinct changes in cellular phosphoinositide levels and stimulates microsomal ATP transport
G Konrad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity
OC Ikonomov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Human VPS34 is required for internal vesicle formation within multivesicular endosomes
CE Futter et al.
JOURNAL OF CELL BIOLOGY (2001)
Generation of high curvature membranes mediated by direct endophilin bilayer interactions
K Farsad et al.
JOURNAL OF CELL BIOLOGY (2001)
SNX3 regulates endosomal function through its PX-domain-mediated interaction with Ptdlns(3)P
Y Xu et al.
NATURE CELL BIOLOGY (2001)
The PX domains of p47phox and p40phox bind to lipid products of Pl(3)K
F Kanai et al.
NATURE CELL BIOLOGY (2001)
Ptdlns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox
CD Ellson et al.
NATURE CELL BIOLOGY (2001)
Phox domain interaction with Ptdlns(S)P targets the Vam7 t-SNARE to vacuole membranes
ML Cheever et al.
NATURE CELL BIOLOGY (2001)
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
A Kihara et al.
JOURNAL OF CELL BIOLOGY (2001)
Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain
E Nielsen et al.
JOURNAL OF CELL BIOLOGY (2000)
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
Y Kamada et al.
JOURNAL OF CELL BIOLOGY (2000)
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
DJ Gillooly et al.
EMBO JOURNAL (2000)
Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction
YX Mao et al.
CELL (2000)
Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways
T Noda et al.
JOURNAL OF CELL BIOLOGY (2000)
Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
A Petiot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)