期刊
FEBS LETTERS
卷 584, 期 7, 页码 1302-1312出版社
WILEY
DOI: 10.1016/j.febslet.2010.01.011
关键词
Autophagy; Phosphoinositide; Signalling; Endoplasmic reticulum; PI 3-Kinase
资金
- Biotechnology and Biological Sciences Research Council (BBSRC)
- Biotechnology and Biological Sciences Research Council [BBS/E/B/00001221] Funding Source: researchfish
The simple phosphoinositide phosphatidylinositol 3-phosphate (PI(3)P) has been known to have important functions in endocytic and phagocytic traffic, and to be required for the autophagic pathway. In all of these settings, PI(3)P appears to create platforms that serve to recruit specific effectors for membrane trafficking events. In autophagy, PI(3)P may form the platform for autophagosome biogenesis. (C) 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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